Abstract| Volume 263, e212, August 2017

Statin treatment potentiates the lipid-lowering and anti-atherogenic effect of bat activation by accelerating lipoprotein remnant clearance

      Aim: Activated brown adipose tissue (BAT) reduces both hyperlipidemia and atherosclerosis development via a mechanism that involves the uptake of triglyceride-derived fatty acids by BAT and subsequent accelerated formation of cholesterol-enriched lipoprotein remnants. Hepatic remnant clearance is also stimulated by statins. Therefore, the aim of the current study was to investigate whether statin treatment on top of BAT activation further reduces hyperlipidemia and atherosclerosis development.
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