Aim: Activated brown adipose tissue (BAT) reduces both hyperlipidemia and atherosclerosis
development via a mechanism that involves the uptake of triglyceride-derived fatty
acids by BAT and subsequent accelerated formation of cholesterol-enriched lipoprotein
remnants. Hepatic remnant clearance is also stimulated by statins. Therefore, the
aim of the current study was to investigate whether statin treatment on top of BAT
activation further reduces hyperlipidemia and atherosclerosis development.
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© 2017 Published by Elsevier Inc.