Aim: Activated brown adipose tissue (BAT) reduces both hyperlipidemia and atherosclerosis development via a mechanism that involves the uptake of triglyceride-derived fatty acids by BAT and subsequent accelerated formation of cholesterol-enriched lipoprotein remnants. Hepatic remnant clearance is also stimulated by statins. Therefore, the aim of the current study was to investigate whether statin treatment on top of BAT activation further reduces hyperlipidemia and atherosclerosis development.
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© 2017 Published by Elsevier Inc.