Aim: Interventions or genetic variants that raise HDL cholesterol do not reduce risk of
atherosclerotic cardiovascular disease (ASCVD). Therefore, studies of HDL functionalities
rather than HDL cholesterol levels are encouraged. We previously reported that cholesterol
efflux capacity was independently and inversely associated with the presence of ASCVD
in 227 familial hypercholesterolemia (FH) patients. Accordingly, we aimed to investigate
the association between antioxidant property of HDL, another functionality, and the
presence of ASCVD in 332 statin-treated heterozygous FH patients.
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© 2017 Published by Elsevier Inc.
