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Update on peripheral artery disease: Epidemiology and evidence-based facts

  • Jun Shu
    Affiliations
    Department of Medicine, Albert Einstein College of Medicine, Montefiore University Hospital, New York, NY, USA
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  • Gaetano Santulli
    Correspondence
    Corresponding author. Department of Medicine, Albert Einstein College of Medicine, Montefiore University Hospital, New York, NY, USA.
    Affiliations
    Department of Medicine, Albert Einstein College of Medicine, Montefiore University Hospital, New York, NY, USA
    Department of Biomedical Advanced Sciences, “Federico II” University, Naples, Italy
    Search for articles by this author
      Peripheral artery disease (PAD) is a progressive disorder characterized by stenosis and/or occlusion of large and medium-sized arteries, other than those that supply the heart (coronary artery disease, CAD) or the brain (cerebrovascular disease). PAD affects the lower extremities more commonly than the upper extremity vessels, and may lead to an recurrent fatigue, cramping sensation, or pain that is known as claudicatio intermittens (intermittent claudication), which is the most recognized symptomatic subset of lower extremity PAD.

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