Abstract| Volume 275, e21, August 2018

Metabolically activated and classically activated pro-inflammatory M1 macrophages exhibit divergent effects on ABCA1 cholesterol efflux capacity

      Aim: Pro-inflammatory M1 macrophages exhibit differential expression of plasma membrane proteins depending upon their micro-environment. In this study we questioned how macrophage cholesterol efflux capacity is affected under classically inflamed (LPS+IFNg) (MM1) versus metabolically activated (high glucose, palmitate and insulin) (MMe) environments.
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