Vascular Biology - Session 2| Volume 275, e48, August 2018

Transcriptome analysis of human macrophages reveals genes regulating cellular cholesterol efflux

      Aim: HDL plays an important role in cholesterol metabolism through a mechanism known as reverse cholesterol transport. In this study, we applied a bioinformatics approach to identify genes that change their expression in macrophages upon exposure to HDL. Furthermore, we evaluated the role of such genes in cellular cholesterol efflux mediated by HDL.
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