Aim: 5-Lipoxygenase (5-LO)-leukotriene B4 (LTB4) signalling axis plays an important role
in vascular inflammation, however, the cellular source of LTB4 in the injured vasculatures
is unclear. To determine the hypothesis that vascular smooth muscle cells (VSMC) might
be an active player in the secretion of LTB4 in the injured vasculatures, we examined
LTB4 production and related signaling mechanisms in VSMC stimulated with HMGB1, a
damage-associated molecular pattern.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to AtherosclerosisAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
Article info
Publication history
P1.4.086bis
Identification
Copyright
© 2018 Published by Elsevier Inc.
