Aim: Familial hypercholesterolemic (FH) patients show qualitative abnormalities in the
HDL particles that may be critical for HDL remodeling and macrophage cholesterol efflux.
In the present study, we evaluated the HDL-associated master remodeling lipid transfer
proteins and enzymes and their potential to alter HDL composition and macrophage cholesterol
efflux in non-treated FH subjects with an identified LDLR mutation and in normolipidemic
subjects matched for age and sex.
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P2.5.218
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© 2018 Published by Elsevier Inc.
