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Abstract| Volume 275, e171, August 2018

Adequate glycemic control prevents cholesterol efflux impairment and lipid accumulation in macrophages induced by advanced glycated albumin

      Aim: Advanced glycation end products (AGE) predict the development of atherosclerosis. AGE-albumin from poorly controlled diabetes mellitus (DM) patients impairs macrophage cholesterol efflux by reducing ABCA-1. We analyzed if an adequate glycemic control (aGC) is able to prevent alterations in cholesterol efflux elicited by DM-albumin.
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