Highlights
- •Low HDL is the most common type of dyslipidemia in middle-aged and older Chinese.
- •The prevalence of dyslipidemia is the highest in North China.
- •The awareness, treatment and control of dyslipidemia are poor in Southwest China.
Abstract
Background and aims
Unevenly socioeconomic development and nutrition transition might bring large variations
in the epidemiology of dyslipidemia. We aimed to estimate the prevalence, awareness,
treatment and control of dyslipidemia in different socioeconomic statuses and geographic
regions in China, and to assess the associated factors and comorbidities of dyslipidemia.
Methods
We included participants aged 45 years and above from a nationally representative
investigation: the China Health and Retirement Longitudinal Study 2011. Dyslipidemia
was defined based on the 2016 guideline of Chinese Prevention and Treatment of Dyslipidemia
in adults. Multivariable logistic regression was adopted to assess the potentially
associated factors and commodities of dyslipidemia.
Results
In 2010, the prevalence of dyslipidemia was 42.84% among people aged 45 years and
above. Low level of high-density lipoprotein cholesterol (HDL-C) was the most common
type of dyslipidemia. The awareness, treatment and control rates among dyslipidemic
subjects were 20.27%, 14.41% and 4.94%, respectively. In dyslipidemic patients who
were under treatment, the control rate was 34.26%. People aged 50–59 years were at
a significantly higher risk of dyslipidemia than those aged 45–49 years. Male gender,
living in North China, overweight, obesity, central obesity, hypertension, diabetes
and hyperuricemia were significantly associated with a higher risk of dyslipidemia.
Current alcohol drinking and underweight were linked to a lower prevalence of dyslipidemia.
Conclusions
Our study revealed a high prevalence of dyslipidemia among middle-aged and older Chinese.
The awareness, treatment and control rates were far from ideal and geographic inequality
was highlighted. More efforts are needed to prevent and manage dyslipidemia in China.
Graphical abstract

Graphical Abstract
Keywords
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Article info
Publication history
Published online: January 19, 2019
Accepted:
January 9,
2019
Received in revised form:
December 10,
2018
Received:
September 11,
2018
Identification
Copyright
© 2019 Elsevier B.V. All rights reserved.