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Seasonal variations of lipid profiles in a French cohort

      We read with interest the article by Vedel-Krogh et al. [
      • Vedel-Krogh S.
      • et al.
      The Christmas period holidays are immediately followed by a period of hypercholesterolemia.
      ] showing that celebrating the Danish “hygge” is associated with higher concentrations of total (TC) and low-density lipoprotein cholesterol (LDL-C) among 25,764 individuals from the Copenhagen General Population Study. They concluded to not screen and/or diagnose for a possible hypercholesterolemia around Christmas period. They stress the need for re-testing patients later and certainly prior to initiating a cholesterol-lowering therapy. They also pointed out that these results may not be applied to other European populations, which do not celebrate the Danish “hygge”. Therefore, we tested this hypothesis among participants from Constances, the largest French population-based study [
      • Zins M.
      • et al.
      The French CONSTANCES population-based cohort: design, inclusion and follow-up.
      ] and extended the analyses to triglycerides (TGs) and according to sex.

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      References

        • Vedel-Krogh S.
        • et al.
        The Christmas period holidays are immediately followed by a period of hypercholesterolemia.
        Atherosclerosis. 2019; 281: 121-127
        • Zins M.
        • et al.
        The French CONSTANCES population-based cohort: design, inclusion and follow-up.
        Eur. J. Epidemiol. 2015; 30: 1317-1328
        • Catapano A.L.
        • et al.
        ESC/EAS Guidelines for the management of dyslipidaemias.
        Eur. Heart J. 2016; 39: 2999-3058

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