Background and Aims: Macrophages are one of the critical drivers of atherosclerotic plaque inflammation,
which may be beneficial in early disease stages, but later more detrimental. The latter
effects could potentially be halted by re-instructing plaque macrophages towards an
anti-inflammatory, inflammation-resolving phenotype. Therefore, we aim to identify
key genes in atherosclerosis that skew macrophages from pro- towards an anti-atherogenic
phenotypes.
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Article info
Publication history
Published online: August 03, 2019
EAS19-0937Identification
Copyright
© 2019 Published by Elsevier Inc.
