Background and Aims: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are reported to
degrade LDL receptors and thereby prevent hypercholesterolemia. Thus, regulation of
PCSK9 levels might prevent the onset of dislipidemia. However, little is known if
food ingredients can regulate circulating PCSK9 levels. D-Allulose, an epimer of D-fructose,
is one of rare sugars and is a non-caloric sweetener having several health benefits,
including suppression of increased serum glucose levels and fat accumulation. However,
the effects of D-allulose on cholesterol metabolism are unclear. Here, we examined
the effects of D-allulose on PCSK9 levels and cholesterol metabolism in Golden Syrian
hamsters.
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Publication history
Published online: August 05, 2019
EAS19-0578Identification
Copyright
© 2019 Published by Elsevier Inc.
