- •Population aging is rapidly increasing worldwide, especially in developing countries.
- •Incidence and mortality due to cardiovascular diseases are extremely high in the very elderly population.
- •There is no specific algorithm for the atherosclerotic cardiovascular disease risk estimation in very elderly individuals.
- •It is important to assess the main risk factors that could lead very elderly individuals to manifest atherosclerotic disease, to adopt a prevention strategy.
Background and aims
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- An estimate of the worldwide prevalence and disability associated with osteoporotic fractures.Osteoporos. Int. 2006; 17: 1726-1733https://doi.org/10.1007/s00198-006-0172-4
- Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.Lancet. 2015; 385: 117-171https://doi.org/10.1016/S0140-6736(14)61682-2
- An aging world: 2015.(Washington)https://www.census.gov/content/dam/Census/library/publications/2016/demo/p95-16-1.pdfDate: 2016Date accessed: September 11, 2017
- Meta-analysis: excess mortality after hip fracture among older women and men.Ann. Intern. Med. 2010; 152: 380https://doi.org/10.7326/0003-4819-152-6-201003160-00008
- The link between osteoporosis and cardiovascular disease., Clin. Cases Miner.Bone Metab. 2008; 5: 19-34http://www.ncbi.nlm.nih.gov/pubmed/22460842Date accessed: January 10, 2018
- Health ABC Study, the association of bone mineral density measures with incident cardiovascular disease in older adults.Osteoporos. Int. 2007; 18: 999-1008https://doi.org/10.1007/s00198-007-0338-8
- Coronary microvascular endothelial dysfunction is an independent predictor of development of osteoporosis in postmenopausal women.Vasc. Health Risk Manag. 2014; 10: 533https://doi.org/10.2147/VHRM.S63580
- Osteoprotegerin gene polymorphisms in men with coronary artery disease.J. Clin. Endocrinol. Metab. 2004; 89: 3764-3768https://doi.org/10.1210/jc.2003-032054
- Osteopontin in cardiovascular disease.Cardiol. Rev. 2010; 18: 125-131https://doi.org/10.1097/CRD.0b013e3181cfb646
- Association of systemic inflammatory activity with coronary and carotid atherosclerosis in the very elderly.Atherosclerosis. 2011; 216: 212-216https://doi.org/10.1016/j.atherosclerosis.2011.01.040
- American Cancer Society guidelines for the early detection of cancer, 2006.Ca - Cancer J. Clin. 2006; 56: 11-50
- Global recommendations on physical activity for health.Geneva World Health Org. 2010; https://doi.org/10.1080/11026480410034349
- Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis.Lancet. 1992; 340: 1111-1115
- American Society of Echocardiography, American Society of Echocardiography recommendations for use of echocardiography in clinical trials.J. Am. Soc. Echocardiogr. 2004; 17: 1086-1119https://doi.org/10.1016/j.echo.2004.07.013
- Cardiology patient page. Use of new imaging techniques to screen for coronary artery disease.Circulation. 2003; 108: e50-e53https://doi.org/10.1161/01.CIR.0000085363.88377.F2
- Assessing the nutritional status of the elderly: the Mini Nutritional Assessment as part of the geriatric evaluation.Nutr. Rev. 1996; 54: S59-S65
- Global Recommendations on Physical Activity for HealthGeneva: World Health Organization. 978 92 4 159 997 92010
- Osteoporosis, osteopenia, and atherosclerotic vascular disease.Arch. Med. Sci. 2011; 7: 21-26https://doi.org/10.5114/aoms.2011.20599
- Bone loss and the progression of abdominal aortic calcification over a 25 year period: the Framingham Heart Study.Calcif. Tissue Int. 2001; 68: 271-276http://www.ncbi.nlm.nih.gov/pubmed/11683533Date accessed: April 25, 2018
- Carotid plaque echogenicity and risk of nonvertebral fractures in women: a longitudinal population-based study.Calcif. Tissue Int. 2006; 79: 207-213https://doi.org/10.1007/s00223-006-0071-x
- Bone mineral density and the risk of peripheral arterial disease: the rotterdam study.Calcif. Tissue Int. 2002; 70: 443-449https://doi.org/10.1007/s00223-001-2076-9
- Evaluation of cardiovascular risk factors and bone mineral density in post menopausal women undergoing coronary angiography.Int. J. Cardiol. 2008; 131: 66-69https://doi.org/10.1016/j.ijcard.2007.09.002
- The association between low bone mass at the menopause and cardiovascular mortality.Am. J. Med. 1999; 106: 273-278http://www.ncbi.nlm.nih.gov/pubmed/10190374Date accessed: April 25, 2018
- Rate of bone loss is associated with mortality in older women: a prospective study.J. Bone Miner. Res. 2000; 15: 1974-1980https://doi.org/10.1359/jbmr.2000.15.10.1974
- Relationship between lipids and bone mass in 2 cohorts of Healthy women and men.Calcif. Tissue Int. 2004; 74: 136-142https://doi.org/10.1007/s00223-003-0050-4
- Leisure time but not occupational physical activity significantly affects cardiovascular risk factors in an adult population.Eur. J. Clin. Investig. 2007; https://doi.org/10.1111/j.1365-2362.2007.01884.x
- Exercise, vascular wall and cardiovascular diseases: an update (Part 2).Sport. Med. 2009; https://doi.org/10.2165/00007256-200939010-00004
- American college of sports medicine, American college of sports medicine position stand: physical activity and bone health.Med. Sci. Sport. Exerc. 2004; 36: 1985-1996