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Abstract| Volume 315, e66, December 2020

High lysophosphatidylcholine and low phosphatidylcholine concentrations in HDL phospholipids are associated with atherosclerosis in relation to decreased cholesterol efflux capacity

      Background and Aims: Cholesterol efflux capacity (CEC) may be a more important risk marker than plasma HDL cholesterol levels. However, developing a standardized clinical laboratory test for measuring CEC would be extremely difficult because cell lines and pooled plasma are specific to each institution. The aim of this cross-sectional study was to identify phospholipid (PL) components of HDL, which are predictive of both decreased CEC and atherosclerosis severity, in order to develop novel standardized biomarkers as alternatives to CEC.
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