Background and Aims: Familial Hypercholesterolemia (FH) is a genetic disease characterized by premature
Arteriosclerotic Cardiovascular Disease (ASCVD). Low Density Lipoproteins (LDLs) may
be subdivided into two main fractions: large-buoyant (lbLDL) and small-dense (sdLDL)
particles, with different metabolic behaviour and atherogenicity. In a similar manner
High Density Lipoproteins (HDLs) may be separated into subpopulations of different
size and composition. Aim of the present study is the evaluation of LDL and HDL subfractions
in FH patients, tring to identify their predicting value in cardiovascular disease
onset and the effects of lipid-lowering treatment.
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Publication history
448 / #1063 Poster 2. LIPIDS AND LIPOPROTEINS / 2.3 HDL 10-05-2020 8:30 AM - 7:00 PM
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© 2020 Published by Elsevier Inc.
