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Abstract| Volume 355, P160, August 2022

Lipid disorders in young obese patients depending on smoking status

  • E.N. Livantsova
    Affiliations
    Department Of Cardiovascular Pathology And Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russian Federation
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  • Y.R. Varaeva
    Affiliations
    Department Of Cardiovascular Pathology And Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russian Federation
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  • P.A. Kelekhsaev
    Affiliations
    Department Of Cardiovascular Pathology And Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russian Federation

    Department Of Intermediate Level Therapy, Pirogov Russian National Research Medical University, Moscow, Russian Federation
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  • T.D. Kiknadze
    Affiliations
    Department Of Cardiovascular Pathology And Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russian Federation
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  • G.E. Leonov
    Affiliations
    Department Of Cardiovascular Pathology And Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russian Federation
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  • A.V. Starodubova
    Affiliations
    Department Of Cardiovascular Pathology And Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russian Federation

    Department Of Intermediate Level Therapy, Pirogov Russian National Research Medical University, Moscow, Russian Federation
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      Background and Aims : Our study aims to evaluate the association between lipid parameters and smoking status in obese patients.
      Methods: 19 young obese adults (mean age 35.2 years) were examined. We collected the data of anthropometry, body composition analysis, biochemical markers, and lipid profile.
      Results: We included 42.1% non-smokers, 42.1% current smokers, and 15.8% ex-smokers. The proportion of women was 68%. The average BMI was 34.0 kg/m2. Lipid parameters were comparable in three groups (median total cholesterol: 5.3 mmol/L, 5.2 mmol/L, and 5.6 mmol/L; median LDL cholesterol: 3.5 mmol/L, 3.6 mmol/L, and 3.9 mmol/L for non-smokers, current smokers, and ex-smokers, respectively). Hypercholesterolemia was found in 11 (58%) patients: 4 (50%) non-smokers and 5 (62.5%) current smokers. Hyper-LDL-C was detected in 10 (52.6%): 3 (37.5%) non-smokers and 5 (62.5%) current smokers.
      Conclusions: The results of our study confirm the important contribution of smoking to dyslipidemias for young people. Further research is required to clarify the features of smoking-associated metabolic disorders. Funding: Research work was carried out at the expense of a subsidy for the implementation of the state task within FR No. 0410-2022-0005 and АSR No. 0410-2020-0003. Disclosure of Interest: None Declared