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Métabolisme des phospholipides de l'aorte

Incorporation de [32P]orthophosphate dans les phospholipides aortiques du rat in vivo
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      Summary

      The rate of 32P incorporation into the phospholipids of rat plasma and aorta was studied in vivo from 4 to 14 hours. While the rate of incorporation is similar during the first 4 hours, after that time it becomes greater in plasma phospholipids than in those of the aorta.
      The rate of incorporation of 32P into sphingomyelin and phosphatidylethanolamine is higher in plasma than in aorta.
      For phosphatidylinositol the maximum of incorporation is reached much later in plasma than in aortic tissue.
      While phosphatidylglycerol is not detected in plasma, this phospholipid shows a high specific activity in aorta and is rapidly labelled.
      The specific activities of phosphatidylcholine and lysophosphatidylcholine are higher in rat plasma than in aorta and are very similar, whereas in aortic tissue phosphatidylcholine is more highly labelled than lysophosphatidylcholine and in our experiments only reached its maximum specific activity after about 14 hours.
      Comparisons between phospholipid turnover in rat plasma and aorta gave evidence of the metabolic activity of aortic tissue.

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