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Arteriosclerosis with metastatic calcification in corriedale sheep in Punjab

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      Summary

      An unusual disease has been observed in about 90% of sheep at the breeding farm at Mattewara, Ludhiana, India. Fifty-three out of 57 adult Corriedale sheep examined after death showed plaque formation in the aorta and other arteries. Histopathological examination revealed intense calcification of the medial layer and proliferation of intimal connective tissue. In some cases the lung and kidney also showed calcareous deposits. Analysis of blood plasma revealed a slight rise in the calcium level during the months of June, November and December. Phosphorus values were found to vary up to high normal limits in most of the animals. The disease is suspected to be due to ingestion of some poisonous plant, with effects similar to those of Solanum malacoxylon which is known to cause enteque seco disease in sheep in Argentina.

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