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The relationship between employment grade and plasma fibrinogen level among Japanese male employees

  • Masao Ishizaki
    Correspondence
    Corresponding author. Tel.: +44-171-5045629; fax: +44-171-8130242
    Affiliations
    Department of Epidemiology and Public Health, International Centre for Health and Society, University College London Medical School, 1–19 Torrington Place, London WC1E 6BT, UK

    Health Care Center, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa 920-0293, Japan
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  • Pekka Martikainen
    Affiliations
    Department of Epidemiology and Public Health, International Centre for Health and Society, University College London Medical School, 1–19 Torrington Place, London WC1E 6BT, UK

    Department of Sociology, Population Research Unit, P.O. Box 18, FIN-00014, University of Helsinki, Helsinki, Finland
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  • Hideaki Nakagawa
    Affiliations
    Department of Public Health, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa 920-0293, Japan
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  • Michael Marmot
    Affiliations
    Department of Epidemiology and Public Health, International Centre for Health and Society, University College London Medical School, 1–19 Torrington Place, London WC1E 6BT, UK
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  • on behalf of the YKKJ Research Group

      Abstract

      Plasma fibrinogen is an important risk factor for cardiovascular disease, and is associated with socioeconomic status in Europe and the United States. We evaluated whether the relationship between socioeconomic status and plasma fibrinogen level exists in Japanese male employees, and whether this relationship is independent of other correlates of plasma fibrinogen. This cross-sectional study was conducted on full-time male employees aged 20–58 in a metal-products factory between April 1996 and March 1997. Altogether 4375 employees (92.9%) participated. Low employment grade and low educational background were associated with increased age-adjusted plasma fibrinogen level. Adjusting for body mass index, waist to hip ratio, height, smoking habit, alcohol consumption, physical activity at leisure and systolic blood pressure did not attenuate these associations much. Adjusting for white blood cell count and hemoglobin A1c reduced the associations of both employment grade and educational background with plasma fibrinogen level, nevertheless these relationships remained significant.

      Keywords

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